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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

NARSAD Young Investigator Grantee, Garret Stuber, Ph.D. of University Of North Carolina School Of Medicine, expert on anxiety disorders and depression
Garret Stuber, Ph.D.
April 01, 2013

Researchers at the University Of North Carolina School Of Medicine have identified for the first time how two brain regions interact to promote emotionally motivated behaviors associated with anxiety and reward. The...

Brain research, schizophrenia research
Brain Research
March 29, 2013

Many people with schizophrenia struggle to think clearly and remember information, and these problems prevent many from living and working independently. How these difficulties arise in the first place remains mysterious...

NARSAD Grantee Eric M. Morrow, M.D., Ph.D. of Brown University, Expert on autism research
Eric M. Morrow, M.D., Ph.D.
March 28, 2013

NARSAD Grantee Eric M. Morrow, M.D., Ph.D. of Brown University and his collaborators have identified a new genetic pathway linked to autism. The research team studied rare forms of autism and found that two genes...

Gail L. Daumit, M.D., M.H.S., Expert in depression, bipolar disorder and schizophrenia, and mental illness
Dr. Gail L. Daumit
March 22, 2013

NARSAD Grantees Gail L. Daumit, M.D., M.H.S., Faith B. Dickerson, Ph.D., M.P.H., and Richard W. Goldberg, Ph.D., launched the first weight loss clinical trial to include people with serious mental illnesses. Project “...

 Bryan L. Roth, M.D., Ph.D., Foundation Scientific Council Member, received a NARSAD Young Investigator Grant in 1992 for work on serotonin receptors
Dr. Bryan L. Roth
March 21, 2013

Bryan L. Roth, M.D., Ph.D., Foundation Scientific Council Member, received a NARSAD Young Investigator Grant in 1992 to study the structure and function of serotonin receptors. At the time, he was having difficulty...

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