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Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Jeffrey Borenstein, M.D. President and CEO of the Brain & Behavior Research Foundation in Washington D.C. at the White House
Jeffrey Borenstein, M.D.
June 04, 2013

The Brain & Behavior Research Foundation was a participant at the White House for yesterday’s historic convening of a National Conference on Mental Health. Foundation President Jeffrey Borenstein, M.D. was among the...

NARSAD Grantee Kirsty Spalding, Ph.D. from the Karolinska Institute in Stockholm, Sweden, Expert on depression and brain research
Kirsty Spalding, Ph.D.
June 18, 2013

It was believed for a long time that the human brain didn’t change much once mature. That belief has been turned on its head over the course of the past fifteen years. Brain & Behavior Research Foundation NARSAD...

Karl Deisseroth, M.D., Ph.D., Stanford University, brain research expert and inventor of optogenetics
Karl Deisseroth, M.D., Ph.D.
June 14, 2013
  Rewards can be powerful teachers, but it is actually the surprising moments—when an anticipated reward does not come, or when one arrives unexpectedly—that drive the brain to learn. The brain chemical dopamine has been...
Helen S. Mayberg, M.D., of Emory University, an expert on depression
Helen S. Mayberg, M.D.
June 13, 2013
  Brain & Behavior Research Foundation Scientific Council Member and three-time NARSAD Grantee Helen S. Mayberg, M.D., was principal investigator for a study that showed that specific patterns of brain activity can help...
Susanne Ahmari, M.D., Ph.D., expert on obsessive-compulsive disorder
Susanne Ahmari, M.D., Ph.D.
June 11, 2013

In two back-to-back papers published June 7, 2013 in Science, two different research teams used the groundbreaking fiber-optic light technology, optogenetics, developed by Karl Deisseroth, M.D., Ph.D., with the support of...

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