Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Jin Fan, Ph.D., assistant professor of psychiatry at the Mount Sinai School of Medicine
Jin Fan, Ph.D.
November 02, 2012

Jin Fan, Ph.D., assistant professor of psychiatry at the Mount Sinai School of Medicine in New York, used his NARSAD Young Investigator Grant to help identify where human empathy is centered in the brain: the area known...

Michael O’Donovan, M.D., Ph.D., Cardiff University Medical, Schizophrenia Expert
Michael O’Donovan, M.D., Ph.D.
November 01, 2012

The Brain & Behavior Research Foundation celebrated 25 years of Empowering Research for Productive Lives and honored eight extraordinary scientists at its Annual National Awards Dinner in New York City on October 26....

Stanislav Zakharenko, M.D, Ph.D., St. Jude Children's Research Hospital, Expert in Schizophrenia
Stanislav Zakharenko, M.D, Ph.D.
October 15, 2012

NARSAD Young Investigator Grantee, Stanislav Zakharenko, M.D, Ph.D., along with colleagues in his laboratory at St. Jude Children's Research Hospital, has identified a molecular pathway that may play a role in...

Maria Karayiorgou, M.D., Professor of psychiatry at Columbia University Medical Center and acting chief, divisatric and Medical Genetics, New York State Psychiatric Institute
Maria Karayiorgou, M.D.
October 11, 2012

NARSAD Distinguished Investigator Grantee,  Maria Karayiorgou, M.D., and NARSAD Young Investigator Grantee, Joseph A. Gogos, M.D., Ph.D, are the authors of a new study that identified dozens of new gene mutations that...

 Consuelo Walss-Bass, Ph.D., 2004 and 2007 NARSAD Young Investigator Grantee, Associate Professor Department of Psychiatry, University of Texas Health Science Center at San Antonio, Expert on Schizophrenia
Consuelo Walss-Bass, Ph.D.
September 24, 2012

Isolated populations with relatively homogeneous gene pools make excellent natural laboratories for genetic research. One such study examines the genetics of schizophrenia. This research focuses on the descendents of a...

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