Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Dolores Malaspina, M.D., NARSAD Young Investigator Grantee, Jay Adam Gingrich, M.D., Ph.D.,  NARSAD Distinguished Investigator Grantee, Eric J. Nestler, M.D., Ph.D.
Drs. Malaspina, Gingrich, and Nestler
September 24, 2012

A recent New York Times article titled "Why Fathers Really Matter" cites the work of three NARSAD Grant-funded researchers.

The article reports that a recent comprehensive study advances earlier NARSAD Grant-...

The New York Time - Autism, Schizophrenia
The New York Times
August 23, 2012

Work that was done as early as the 1990s has found new reinforcement with a new study published online in the journal Nature on August 22, 2012. In 2001, four-time NARSAD Grantee, Dolores Malaspina, M.D., M.P.H. published...

Zhiping Pang, Ph.D., Robert Wood Johnson Medical School University of Medicine & Dentistry of New Jersey
Zhiping Pang, Ph.D.
August 07, 2012

Zhiping Pang, Ph.D., Assistant Professor of Neuroscience and Cell Biology at UMDNJ-RWJMS-Child Health Institute of New Jersey won the 2012 Freedman Prize on July 27, 2012 for his development of a novel way to study...

Mikhail V. Pletnikov, M.D., Ph.D., associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, expert on schizophrenia
Mikhail Pletnikov, M.D., Ph.D.
July 20, 2012

In a new study published in the journal Molecular Psychiatry, Johns Hopkins researchers have discovered that two previously established biological risk factors for schizophrenia have a cause-and-effect relationship....

Patrick F. Sullivan, M.D., Professor and Director of Psychiatric Genonomics at the University of North Carolina School of Medicine, Autism, Schizophrenia, Bipolar Disorder
Patrick F. Sullivan, M.D.
July 05, 2012

A new study published online in the Archives of General Psychiatry on July 2 found that a family history of schizophrenia and/or bipolar disorder is a risk factor for autism.

Patrick F. Sullivan, M.D., Professor...

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