Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

NARSAD Grantee Robert Freedman, M.D., Professor and Chairman, Department of Psychiatry and Pharmacology, University of Colorado and Editor of The American Journal of Psychiatry, expert on schizophrenia
Robert Freedman, M.D.
January 15, 2013

According to a new study by a research team that includes NARSAD Grantees Robert Freedman, M.D., Randal G. Ross, M.D., Sherry Leonard, Ph.D. and Karen E. Stevens, Ph.D., choline, an essential nutrient, shows promise for...

Brain & Behavior Research Foundation NARSAD Grantee Anne S. Bassett, M.D., FRCPC, Professor of Psychiatry, University of Toronto and Canada Research Chair in Schizophrenia Genetics, expert on schizophrenia
Anne S. Bassett, M.D., FRCPC
January 14, 2013

A pilot study led by Brain & Behavior Research Foundation NARSAD Grantee Anne S. Bassett, M.D., FRCPC of the University of Toronto and colleagues, shows a positive response to genetic counseling for individuals with...

2012 Highlights: A Sampling of NARSAD Grants at Work
2012 Research Highlights
December 27, 2012

The Brain & Behavior Research Foundation concludes its 25th year of awarding NARSAD Grants that have led to thousands of scientific achievements to improve the lives of those with mental illness. The Foundation...

Ariel V. Deutch, Ph.D. Professor of Psychiatry and Pharmacology Director, National Parkinson Foundation Center of Excellence Vanderbilt University Medical Center Brain & Behavior Research Foundation Scientific Council Member 1997 NARSAD Distinguished Investigator Grantee, Expert on Schizophrenia
Ariel V. Deutch, Ph.D.
December 17, 2012

Over more than a century, neuroscientists have built a framework for studying how the brain works based on the neuron doctrine, which states that nerve cells, or neurons, communicate across a tiny gap, the synapse....

2005 NARSAD Young Investigator Grantee, Christine I. Hooker, Ph.D., now an Associate Professor in Psychology at Harvard, expert on schizophrenia
Christine I. Hooker, Ph.D.
December 17, 2012

Schizophrenia-associated deficits in cognition are not substantially improved by medication, but have been shown to improve with remedial cognitive training. The mechanisms that support this improvement have been largely...

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