Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Jeffrey Lieberman, M.D.
Jeffrey Lieberman, MD
July 26, 2011

Foundation Scientific Council Member Jeffrey Lieberman, M.D. leads team in recent study using magnetic resonance imaging (MRI) data to measure the thickness of the cortex in specific regions of the brain in schizophrenia...

Dr. Guy A. Rouleau
Dr. Guy A. Rouleau
July 11, 2011

Guy A. Rouleau, M.D., Ph.D., Brain & Behavior Research Foundation Distinguished Investigator and colleagues, have discovered the presence of genetic mutations in schizophrenia patients but not their parents.

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Jonathon Robbins
Jonathon Robbins
June 13, 2011

My beautiful son Jonathon committed suicide on April 28th, 2010, after being diagnosed with schizophrenia and depression. He was only 22. I love Jonathon so much and I feel it is my job as his mommy to make the ripple...

Sohee Park, Ph.D.
Sohee Park, Ph.D.
May 26, 2011

Foundation Grantee Sohee Park, Ph.D., and colleagues at Vanderbilt University have discovered that impairments in a brain area involved in perception of social stimuli may be partly responsible for the difficulty...

Bryan Roth, M.D., Ph.D.
Bryan Roth, M.D., Ph.D.
May 01, 2011

"What's most hopeful about our field today is the fact that we have the technologies in hand that will get the answers to mental illness in ways never before possible," says Bryan Roth, M.D., Ph.D., and member of the...

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