Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Aaron T. Beck, M.D. emeritus prof., Dept. of Psych. at the UPENN
Aaron T. Beck, M.D.
March 23, 2012

NARSAD distinguished Investigator Grantee, Aaron T. Beck, the 'Father of Cognitive Behavioral Therapy (CBT)’ proved that it can be used to help treat the 'negative' symptoms of schizophrenia. CBT was invented by Beck in...

Matthew M. Kurtz, PhD NARSAD Young Investigator Grantee Wesleyan University, Schizophrenia
Matthew M. Kurtz, PhD
March 21, 2012

We know that there are large differences in outcome between people with schizophrenia, and there is evidence that these differences may be related to differences in cognitive skills such as the ability to pay attention,...

Sophia Vinogradov, M.D.
Sophia Vinogradov, M.D.
March 20, 2012

A hallmark symptom of schizophrenia is difficulty in distinguishing external reality from internal experiences. Whether or not this impairment is irreversible has long been debated. Now, a pilot study at the University of...

Neil Barber, lives with schizophrenia
Neil Barber
March 20, 2012

The summer before Neil Barber’s junior year in high school, he and three of his buddies decided to experiment with marijuana. Neil’s dad, Greg, recalls the four of them getting “pretty rocked,” but Neil being the only one...

Sophia Vinogradov, M.D.
Sophia Vinogradov, M.D.
March 19, 2012
“Back to Reality: Computerized Cognitive Training Lends a Hand to Schizophrenia” reads the post on the Schizophrenia Research Forum (SRF). The post refers to the recent article published in Neuron summarizing the results of...

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