Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Daniel R. Weinberger, M.D.
Daniel R. Weinberger, M.D.
March 02, 2012

In 2006, Scientific Council Member, Daniel R. Weinberger, M.D. and a team of researchers at the National Institute of Mental Health (NIMH), discovered that the presence of a gene known as neuregulin 1 increases the...

Dolores Malaspina, M.D.
Dolores Malaspina, M.D.
March 01, 2012

In 2001, NARSAD Distinguished Investigator Grantee, Dolores Malaspina, M.D. concluded that having an older father increases the risk of developing schizophrenia. Schizophrenia has strong genetic components, including de...

Karuna Subramaniam, Ph.D.
Karuna Subramaniam, Ph.D.
February 29, 2012

NARSAD Grantees from the University of California, San Francisco demonstrate that brain training, specifically in processes such as auditory and visual processing and emotional identification, can vastly improve the...

Mother, Donor – Brain & Behavior Research Foundation
Alan at high school graduation with mom (right) and grandmother (left)
February 23, 2012

My son was first diagnosed with a debilitating form of bipolar disorder when he was 19. His diagnosis was changed eight years later to schizophrenia and he died at the age of 27 and a half.

Alan began to...

Carrie Bearden, Ph.D., 2003/2005 NARSAD Young Investigator Grantee Associate Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior
Carrie Bearden, Ph.D
February 15, 2012

I was very pleased to read Dr. Adrian Preda’s recent blog posting focused on ‘exercising the brain’. I have become increasingly excited about the potential for aerobic exercise to boost neuroplasticity (i.e., the ability...

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