Schizophrenia

Did you know that schizophrenia affects more than 1 percent of the world's population? See NARSAD Grants at work on the latest schizophrenia research

Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder. It is most accurately described as a psychosis - a type of illness that causes severe mental disturbances that disrupt normal thoughts, speech, and behavior. Schizophrenia is believed to be caused by a combination of genetic and environmental factors.

Positive symptoms may include delusions, thought disorders, and hallucinations. People with schizophrenia may hear voices other people don't hear, or believe other people are reading their minds, controlling their thoughts, or plotting to harm them. Negative symptoms may include avolition (a lack of desire or motivation to accomplish goals), lack of desire to form social relationships, and blunted affect and emotion. Cognitive symptoms involve problems with attention and memory, especially in planning and organization to achieve a goal. Cognitive deficits are the most disabling for patients trying to lead a normal life.

Schizohrenia research & FAQs


Visit the Schizophrenia Research Forum, fully sponsored by the Brain & Behavior Research Foundation—a virtual community of scientists collaborating in their quest for causes, improved treatments, and better understanding of schizophrenia.

Visit the Schizophrenia Research Forum for more information about research

Sophia Vinogradov, M.D.
Sophia Vinogradov, M.D.
March 19, 2012
“Back to Reality: Computerized Cognitive Training Lends a Hand to Schizophrenia” reads the post on the Schizophrenia Research Forum (SRF). The post refers to the recent article published in Neuron summarizing the results of...
Judith Rapoport (L) and Mary-Claire King (R)
Drs. Rapoport and King
March 19, 2012

In 2008, Scientific Council Members Mary-Claire King, Ph.D. from the University of Washington—widely known for her discovery of a mutation in a gene she named BRCA1 that led to powerful breast cancer diagnostics—and...

Arturas Petronis, M.D., Ph.D.
Arturas Petronis, M.D., Ph.D.
March 14, 2012

Arturas Petronis, M.D., Ph.D. from the Centre for Addiction and Mental Health in Toronto, led researchers in a study, discovering that biochemical (or ‘epigenetic’) changes can impact the ‘expression’ of genes common in...

Dr. Carol Tamminga (right) receiving the Lieber Prize from Dr. Herbert Pardes, Foundation Scientific Council President
Dr. Carol Tamminga (right) Dr. Herbert Pardes (left)
March 12, 2012

As the Brain & Behavior Research Foundation celebrates 25 Years of Discovery to Recovery, it seems fitting to share a video of a presentation given by Carol A. Tamminga, M.D., the most recent winner of the Lieber...

Daniel R. Weinberger, M.D.
Daniel R. Weinberger, M.D.
March 02, 2012

In 2006, Scientific Council Member, Daniel R. Weinberger, M.D. and a team of researchers at the National Institute of Mental Health (NIMH), discovered that the presence of a gene known as neuregulin 1 increases the...

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