Patients with depression tend to smoke a lot, which led to the idea that nicotine may ease depressive symptoms. Research has shown how the process works. Nicotine binds to particular receptor molecules on the surface of...
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Three-time NARSAD Grantee talks about his groundbreaking work on depression since the 1980s
When did your research career begin, and what made you pursue research on depression in particular?
Over more than a century, neuroscientists have built a framework for studying how the brain works based on the neuron doctrine, which states that nerve cells, or neurons, communicate across a tiny gap, the synapse....
Childhood trauma, such as sexual or physical abuse, domestic violence, neglect or parental loss, can have long-lasting consequences. Researchers are exploring the effects of early trauma on the stress-response systems...
A ‘bottom up’ approach to understanding the brain leads to crucial new discoveries
What causes depression? Experience tells us that people can become depressed when they are under acute or chronic stress...