On CNN: Watch NARSAD-Grant Funded Research (Deep Brain Stimulation) Improve Lives

Printer-friendly versionPrinter-friendly version
Helen Mayberg, M.D.
Helen Mayberg, M.D.

Watch Video Here

Deep Brain Stimulation (DBS) is a newer treatment option for patients with severe depression. Using pulses of current, DBS regulates specific areas of the brain (DBS is often referred to as the 'Pacemaker for the Brain'). Developed in the 1980s, DBS was not used to treat depression until Foundation Scientific Council Member Helen Mayberg, M.D. began her pioneering work with the technology in 2003 with the support of a NARSAD Distinguished Investigator Grant and the findings of her earlier NARSAD-Grant funded work.  DBS is used in the treatment of depression to target an area in the brain Dr. Mayberg found to be an important locus of depression pathology.

20 years ago, Dr. Mayberg used her first NARSAD Young Investigator Grant to investigate brain changes in depressed patients using functional neuroimaging. With the help of a second NARSAD Grant, she went on to identify the subcallosal cingulate--Brodman Area 25--as not only a key conduit of neural traffic that gives rise to emotion, but also as an area that appears overactive in depressed people. In 2002, with a NARSAD Distinguished Investigator Grant, she led breakthrough research when she piloted the use of DBS to target ‘Area 25’.

Today, a new study called BROADEN (Brodmann Area Deep brain Neuromodulation) is taking place at multiple research centers around the country including Vanderbilt University Medical Center, University of Texas Southwestern Medical Center in Dallas, Virginia Commonwealth University and the Zucker Hillside Hospital in New York in an attempt to further justify the use of DBS for treatment-resistant depression. Participating in this randomized clinical study are NARSAD Grantees Ronald Salomon, M.D. (Vanderbilt University), Anthony Rothschild, M.D. (University of Massachusetts Medical School), and Stephan Taylor, M.D. (University of Michigan).

To learn more about Deep Brain Stimulation, watch CNN Presents on April 21, 8pm EST to see a great recovery story featuring a woman who was treated by Dr. Mayberg at Emory University for her severe depression.

Sneak Peak:



More info about Dr. Mayberg and her appearance on CNN Presents

Read more about the BROADEN study

To participate in the study visit: www.broadenstudy.com

Article comments

I need help to with psychosis disorder

I can relate to this woman--my depression is so bad that I wish I would die. I feel empty and alienated from everyone many times. My depression is worse than my schizophrenia symptoms! Who can I see in the Norfolk, VA area to do some testing!!!

DBS could possibly help people who have toxoplasmosis and have previously been diagnosed schizo'/effective as this parasite is often found in the brain and is hard to erradicate where could someone go to receive this treatment

What happens when they start experimenting on people who don't ask for help just to test. Or when something goes wrong and causes serious loss of mental state during a normally benign test?

Add new comment

comments

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Please note that researchers cannot give specific recommendations or advice about treatment; diagnosis and treatment are complex and highly individualized processes that require comprehensive face-to- face assessment. Please visit our "Ask an Expert" section to see a list of Q & A with NARSAD Grantees.
By submitting this form, you accept the Mollom privacy policy.