Foundation-Funded Discovery: Patients Can Have Full Relief of Depression by Using Regular Exercise as Second ‘Medication’

NARSAD Independent Investigator Madhukar H. Trivedi, MD and colleagues have discovered that various forms of exercise worked as effectively as adding a second antidepressant medication.

The 4-year controlled study involved patients performing various forms of exercise, journaling and meeting regularly with a psychiatrist. The results demonstrated that medication combined with a regular exercise routine fully relieved the symptoms of major depressive disorder for up to 50% of patients requiring more than one antidepressant.

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