2008 Breakthrough: Important Genetic Links to Schizophrenia Discovered

Printer-friendly versionPrinter-friendly version
Mary-Claire King, Ph.D., Expert in Schizophrenia Research
Mary-Claire King, Ph.D.

In 2008, Foundation Scientific Council Member Mary-Claire King, Ph.D. from the University of Washington—widely known for her discovery of a mutation in a gene she named BRCA1 that led to powerful breast cancer diagnostics— led research teams in the discovery of rare genetic mutations found in high volumes in people with schizophrenia. These mutations―genes that are either deleted or duplicated throughout the genome―are thought to disrupt the brain during development, offering evidence that they could signal susceptibility for developing various mental illnesses (in this case schizophrenia and autism).

Read article in our 2010 issue of Breakthroughs

Read a comprehensive summary of this research from the NIMH

Read the scientific abstract from the April 25, 2008 issue of Science Magazine

Add new comment

comments

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Please note that researchers cannot give specific recommendations or advice about treatment; diagnosis and treatment are complex and highly individualized processes that require comprehensive face-to- face assessment. Please visit our "Ask an Expert" section to see a list of Q & A with NARSAD Grantees.
By submitting this form, you accept the Mollom privacy policy.