Ask an Expert

Eric J. Nestler, M.D., Ph.D. - Brain & behavior expert on anxiety
Q. Based off your mouse studies, do you think that the majority of men who are prone to stress and anxiety are fated to have children with the same issues?
A. No. An individual’s risk for a syndrome as complex and variable as depression or... More >
Katherine L. Wisner, M.D.
Q. How is depression specific to or different in women?
A. “It’s the same rate of occurrence in boys and girls until puberty, when in puberty... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. My father-in-law was treated with radiation for prostate cancer 2 years ago. Since then he seems depressed. He does not believe in therapy. What can we do? Do you think the depression could be caused by something related to his cancer treatment?
A. Depression is often seen in the context of many medical illnesses, including cancer... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on depression
Q. I thought the chemical imbalance theory of depression was a big step forward in treating depression as a bona fide illness. What are the implications of finding that it is out of date and how long until we have new, more effective treatments?
A. There is no doubt that depression is a bona fide illness. Theories are made to be... More >
Katherine L. Wisner, M.D.
Q. What would recovery from depression look like?
A. “A woman who is back to her pre-Depression symptom level, with the ability to... More >
Karl Deisseroth, M.D., Ph.D. - brain & behavior research expert on depression
Q. What advice can you offer to people struggling with severe depression?
A. Karl Deisseroth, M.D., Ph.D., of Stanford University received the Goldman-Rakic... More >
Bruce S. McEwen, Ph.D. - Brain and behavior research expert on depression
Q. My sister lives with depression and seems to be having increasing issues with her memory as well. You say that stress and depression can “shrink” the brain. Can antidepressants and/or other treatments reverse that?
A. Chronic depression is associated with shrinkage of brain areas that are involved in... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Karl Deisseroth, M.D., Ph.D. - Brain and behavior research expert on schizophrenia
Q. Can you envision ways in which the optogenetics technology that you invented might eventually improve the design or use of psychiatric medications?
A. The major challenge we face in psychiatry is understanding. Psychiatric disease... More >
Q. What type of blood pressure medication interferes with Antidepressant LImbitrol?
A. More >
Dr. Katherine L. Wisner, M.D., expert on post-partum depression
Q. What is the difference between ‘baby blues’ and Postpartum Depression?
A. “Distinction between a very brief, tearful, maybe anxious, uncomfortable 4 or 5 days... More >
Karl Deisseroth, M.D., Ph.D. - brain & behavior research expert on depression
Q. What are some recent advancements that have been made in depression research?
A. Karl Deisseroth, M.D., Ph.D., of Stanford University received the Goldman-Rakic... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on depression
Q. Why do some people respond better than others to depression treatments?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
John H. Krystal, M.D.
Q. How long does PTSD last?
A. Length of time varies. According to our diagnostic manual, one must have symptoms... More >
John H. Krystal, M.D.
Q. Where will the breakthroughs come in treating PTSD?
A. “Uniting molecular genetics with brain imaging and psychopharmacology - these sorts... More >
Eric R. Kandel, M.D. - Brain and behavior research expert on PTSD
Q. There is a lot of talk about how to improve memory, but what about erasing traumatic memories from the brains of people that have post-traumatic stress disorder (PTSD)? Is this possible, and if so, do you recommend it?
A. I do not like the idea of erasing memories. I think we can provide someone with... More >
John H. Krystal, M.D.
Q. September 11th is a traumatic date – what do you recommend to manage the stress?
A. It is true that we seem to be bombarded with news related to disasters and social... More >
John H. Krystal, M.D.
Q. What would 'recovery' of PTSD look like?
A. “To be resilient to things they were having trouble coping with … What treatment... More >
John H. Krystal, M.D.
Q. What are exciting new areas of research in PTSD?
A. “Understanding how the brain recovers from stress – the neurobiology of resilience... More >
Fred R. Volkmar, M.D.
Q. What are exciting new areas of research in Autism?
A. “We’re interested in developing new ways to study social development in Autism, new... More >
Fred R. Volkmar, M.D.
Q. What are the general symptoms of autism?
A. “Social troubles … for example in a conversation like we’re having now, a person... More >
Jay N. Giedd, M.D. - brain & behavior research expert on autism
Q. My daughter was diagnosed with autism at age 22. Is this common?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Fred R. Volkmar, M.D.
Q. What would ‘recovery’ from Autism be like?
A. “They’re headed to a path of being independent and self sufficient as adults,... More >

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