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Schahram Akbarian, M.D., Ph.D. Scientific Council Member 1993, 2000 NARSAD Young Investigator Grantee 1997 Klerman Prizewinner Professor of Psychiatry and Neuroscience Chief of the Division of Psychiatric Epigenomics Mount Sinai School of Medicine, Expert on mental illness
Q. If epigenetics is related to environmental influences triggering a susceptibility to mental illness—do you know particular ones leading to schizophrenia?
A. A number of environmental influences acting on the developing brain are suspected to... More >
Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is relapse after stabilization in schizophrenia?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Bryan Roth, M.D., Ph.D.
Q. Is there a link between vitamin D3 deficiency and schizophrenia?
A. There are several studies which have suggested some link between both high and low... More >
Jay N. Giedd, M.D. - brain & behavior research expert on schizophrenia
Q. How common is childhood-onset schizophrenia? What advice can you give a parent?
A. Jay N. Giedd, M.D. of the National Institute of Mental Health received the Ruane... More >
Judith L. Rapoport, M.D. - Brain & behavior research expert on schizophrenia
Q. Are there clear, identifying characteristics of the “abnormal timing of developmental events” that can lead to schizophrenia, psychosis, ADHD, etc.? How can parents know if their child has experienced this abnormal development?
A. This is a top research question. Probably there are very early abnormalities even... More >
Kafui Dzirasa, M.D., Ph.D. - brain & behavior research expert on schizophrenia
Q. What is the next big breakthrough in schizophrenia research?
A. Kafui Dzirasa, M.D., Ph.D., of Duke University Medical Center received the Sidney R... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A. Unfortunately, this is not uncommon, since all forms of severe mental illness are... More >
Husseini K. Manji, M.D.
Q. What will the breakthroughs be in treatment for mood disorders in the next 5 years?
A. The world of neuroscience really is exploding, and I like to say that this is a... More >
Husseini K. Manji, M.D.
Q. Is Ketamine a possible treatment option for bipolar?
A. Ketamine is an experimental treatment for mental health conditions and is not... More >
Andrew A. Nierenberg, M.D. - brain & behavior research expert on bipolar disorder
Q. Are there alternative treatments that might help people with mood disorders?
A. Andrew A. Nierenberg, M.D., of Harvard Medical School received the Colvin Prize for... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a test to diagnose Bipolar Disorder?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on depression
Q. What do you see on the horizon in the next few years as a breakthrough treatment for depression?
A. Several rapidly acting antidepressants are currently in clinical trial, such as... More >
Husseini K. Manji, M.D.
Q. Can anti-seizure medications effectively treat bipolar II disorder?
A. It’s difficult to say without seeing the specific patient involved. As is the case... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is Bipolar Disorder inheritable?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Robert C. Malenka, M.D., Ph.D. - Brain & behavior research expert on bipolar disorder
Q. Our son lives with bipolar disorder and takes 1,000 mg of Depakote® daily. It doesn’t seem to be working; he remains unmotivated and very anxious. He feels no need to seek therapy do you have any advice on how to get someone to visit a therapist?
A. Helping a friend or loved one understand that they will benefit greatly from seeing... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q. In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A. Two areas appear most promising. One is that great progress has been made in... More >
Boris Birmaher, M.D. - brain & behavior research expert on bipolar disorder
Q. Is there a chance that I could pass Bipolar Disorder on to my child?
A. Boris Birmaher, M.D., of the University of Pittsburgh School of Medicine received... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q. Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A. Unfortunately, this is not uncommon, since all forms of severe mental illness are... More >
Husseini K. Manji, M.D.
Q. What advice do you offer for comorbidity (diagnosed with more than one mental illness)?
A. Many people have more than one official diagnosis in mental health, such as... More >
Q. What type of blood pressure medication interferes with Antidepressant LImbitrol?
A. More >
Katherine L. Wisner, M.D.
Q. How is depression specific to or different in women?
A. “It’s the same rate of occurrence in boys and girls until puberty, when in puberty... More >
Katherine L. Wisner, M.D.
Q. What would recovery from depression look like?
A. “A woman who is back to her pre-Depression symptom level, with the ability to... More >
Eric J. Nestler, M.D., Ph.D. - Brain & behavior expert on anxiety
Q. Based off your mouse studies, do you think that the majority of men who are prone to stress and anxiety are fated to have children with the same issues?
A. No. An individual’s risk for a syndrome as complex and variable as depression or... More >
Karl Deisseroth, M.D., Ph.D. - Brain and behavior research expert on schizophrenia
Q. Have any of the labs that are using your invention CLARITY to more precisely observe the brain after death found things that were particularly surprising in your view?
A. Though CLARITY technology is so new that these kinds of studies have not yet been... More >
Bruce S. McEwen, Ph.D. - Brain and behavior research expert on depression
Q. My sister lives with depression and seems to be having increasing issues with her memory as well. You say that stress and depression can “shrink” the brain. Can antidepressants and/or other treatments reverse that?
A. Chronic depression is associated with shrinkage of brain areas that are involved in... More >

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