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Question of the Day

Husseini K. Manji, M.D.
October 31, 2011

The world of neuroscience really is exploding, and I like to say that this is a renaissance in this field. We are learning more and more about the genetics of mental health and also learning more about specific illnesses and their symptomatology, diagnosis and treatments.  I believe we have great potential to treat treatment-resistant depression as well as develop antidepressants that work rapidly.

Similarly, efforts are underway to try to understand “resilience pathways” that could potentially be enhanced to treat the long-term course of bipolar disorder. Unfortunately, new treatment development is very complex and often unpredictable. However, I am optimistic that we will see novel treatments coming through for mood disorders.

 

Husseini K. Manji, M.D.
Scientific Council Member
Global Therapeutic Area Head, Neuroscience
Johnson and Johnson Pharmaceutical Research and Development
Visiting Professor, Duke University

Eric J. Nestler, M.D., Ph.D. - Brain & behavior research expert on schizophrenia
Q Four generations of family, possibly five, have a history that includes severe mental illness. This is not a matter of nurture as we were all raised separately. How common is this? I have chosen to not have children due to this legacy.
A Unfortunately, this is not uncommon, since all forms of severe mental... More >
Rachel G. Klein, Ph.D., Scientific Council Member, 1995 NARSAD Distinguished Investigator Grantee, 2004 Ruane Prize for Outstanding Achievement in Child & Adolescent Psychiatric Research, Professsor of Psychiatry, New York University Child Study Center, Expert on Childhood mental illnesses including ADHD and anxiety
Q In your time on the Scientific Council, what is the most promising area of brain and behavior research you’ve seen?
A Two areas appear most promising. One is that great progress has been made... More >